caption a7 organism dalbavancin mic mbc (ATCC)
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Caption A7 Organism Dalbavancin Mic Mbc, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 10 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 94 stars, based on 10 article reviews
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Article Title: In Vivo Pharmacodynamic Activity of the Glycopeptide Dalbavancin
Journal:
doi: 10.1128/AAC.01264-06
Figure Legend Snippet: In vitro activity of dalbavancin against S. pneumoniae and S. aureus strains
Techniques Used: In Vitro, Activity Assay
Figure Legend Snippet: Serum PKs of dalbavancin in neutropenic infected mice following the administration of six twofold escalating doses ranging from 2.5 to 80 mg/kg intraperitoneally. Each datum point represents the mean and standard deviation for three mice. t1/2, half-life.
Techniques Used: Infection, Standard Deviation
Figure Legend Snippet: Impacts of serum, serum ultrafiltrate, and albumin on in vitro activity of dalbavancin against selected S. aureus strains
Techniques Used: In Vitro, Activity Assay
Figure Legend Snippet: Impacts of single doses of dalbavancin on organism burden in thighs of neutropenic mice infected with either S. pneumoniae ATCC 10813 (left panel) or S. aureus ATCC 29213 (right panel). Mice received either no drug or one of five twofold-increasing dose levels of dalbavancin administered via the intraperitoneal route. The microbiologic burden was determined by plate counts of thigh homogenates at selected time points over 96 h. Each symbol represents a different dose level. Each datum point represents the mean and standard deviation for four thighs.
Techniques Used: Infection, Standard Deviation
Figure Legend Snippet: Impact of dalbavancin dosing interval on the in vivo efficacy of dalbavancin against S. pneumoniae ATCC 10813 (left panel) or S. aureus ATCC 29213 (right panel) in neutropenic mice. Five total dose levels were fractionated over a 144-h study period. Each symbol represents one of four dosing intervals. Each datum point represents the mean and standard deviation log10 CFU/thigh for four thighs.
Techniques Used: In Vivo, Standard Deviation
Figure Legend Snippet: Impact of dalbavancin dosing interval on efficacy against S. pneumoniae and S. aureus
Techniques Used:
Figure Legend Snippet: Relationship between the free-drug 24-h AUC/MIC, Cmax/MIC, and T > MIC and the efficacy of dalbavancin against S. pneumoniae ATCC 10813 (top panel) and S. aureus ATCC 29213 (bottom panel) in the thighs of neutropenic mice over a 144-h treatment period. Each symbol represents the mean log10 CFU/thigh values for four thighs.
Techniques Used:
Figure Legend Snippet: Efficacy of dalbavancin against S. pneumoniae and S. aureus
Techniques Used:
Figure Legend Snippet: Impact of neutrophils on in vivo efficacy of dalbavancin against S. pneumoniae
Techniques Used: In Vivo
Figure Legend Snippet: Dose-response relationship for dalbavancin in the neutropenic murine thigh and lung infection models against S. pneumoniae ATCC 10813 over a 6-day treatment period. Each datum point represents the mean and standard deviation for either two mice (four thighs [triangles]) or three mice (lungs [circles]).
Techniques Used: Infection, Standard Deviation
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